Generally speaking, the brain will usually entrain to the strongest stimulus which would be isochronic tones over binaural beats. So when you see people add binaural beats at a different frequency to the isochronic tones, that would not produce additional brainwave entrainment at another frequency. If they are both at the same frequency I haven’t seen any research to indicate whether that would be beneficial or not, but my belief is that it would weaken the potential for entrainment. When you look at the waveform of an isochronic tone there is a distinct empty space between each beat, making it very pronounced and effective. When you add binaural beats at the same frequency it looks like this: http://www.mindamend.com/wp-content/uploads/2017/11/isochronic-tones-binaural-beats-combined-waveform.jpg. The depth of the waveform is now half as deep and less effective. This is before the binaural beats are formed inside your head, where the waveform is hard to determine and measure. From listening to that type of combination the beats sound much less pronounced, which has to make them much less effective in terms of a brainwave entrainment stimulus, compared to isochronic tones on their own.
Isochronic tones work by influencing your brainwave activity and they can’t directly affect the body. That said, the brain does control the body, so sensations and feelings can sometimes be felt in the body after stimulating your brainwave activity. Some people who are new listeners of this type of audio can sometimes feel tingling sensations in their body. Not everyone feels this and these sensations usually stop once you get more used to using the audios. Isochronic tones are considered as a safe technology. However, sometimes they can leave you feeling temporarily fatigued, especially if you listen to them for an extended period (hours) when you first start using them. If you felt fatigued, I would recommend using them for a much shorter period while you are getting used to them and ensure you are well-hydrated.
Only 4 of the participants reported no change as a result of the stimulation. Four years later in a study (1989) by Anderson analyzed LED photic stimulation for the treatment of headaches. There were 60 patients included in the study which involved Variable Frequency Photo-stimulation (VFP) with specialized goggles that contained light-emitting diodes.
Sleep improvement: There is significant anecdotal evidence that sleep induction and/or quality may be improved as a result of brainwave entrainment. While it is important to consider the placebo effect or simply the effect of a relaxing sound, many people have reported noticeable improvements in their ability to fall asleep and wake up feeling refreshed as a result of entrainment. Entraining frequencies within the slower wave ranges such as alpha, theta, or delta, may help individuals transition more quickly to those states.
There's no doubt that brainwave entrainment audio is a great technology for anyone who is interested in encouraging altered states of consciousness and it certainly can help people to reach deeper states of relaxation than they might normally have access to. I myself will often listen to brainwave entrainment music in order to enhance my practice of meditation. But let’s keep a balanced perspective, put all the marketing hype to one side for a moment and acknowledge that there is no brainwave entrainment technology in this world that can make you meditate like a Zen monk “at the touch of a button”, despite what some might like you to believe. The mind is NOT a machine. It moves through various states of consciousness in an organic way and at a natural pace. We certainly can guide and accelerate that process with the use of brainwave entrainment audio, but we cannot control it with the same sort of specificity and immediacy as you might control the speed of the car you drive.
The formal name for this process is called the “frequency following response”, where the human brain will literally “follow” a specific frequency/beat after being exposed to it for (usually) about 8 minutes. Technically the definitive term “entrainment” does not exactly match the actual process of what is happening to your brain when listening to these audios, but its close enough, and the name has stuck now with these products becoming more popular and widely known.
Entrainment is a term originally derived from complex systems theory, and denotes the way that two or more independent, autonomous oscillators with differing rhythms or frequencies, when situated in a context and at a proximity where they can interact for long enough, influence each other mutually, to a degree dependent on coupling force, such that they adjust until both oscillate with the same frequency. Examples include the mechanical entrainment or cyclic synchronization of two electric clothes dryers placed in close proximity, and the biological entrainment evident in the synchronized illumination of fireflies.